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Single Amino Acid Mutation Decouples Photochemistry of the BLUF Domain from the Enzymatic Function of OaPAC and Drives the Enzyme to a Switched-on State

https://doi.org/10.1016/j.jmb.2023.168312

Tolentino Collado, Jinnette; Bodis, Emoke; Pasitka, Jonatan; Szucs, Mihaly; Fekete, Zsuzsanna; Kis-Bicskei, Nikolett; Telek, Elek; Pozsonyi, Kinga; Kapetanaki, Sofia M.; Greetham, Greg; et al (October 2023, Journal of Molecular Biology)

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Photocycle alteration and increased enzymatic activity in genetically modified photoactivated adenylate cyclase OaPAC

https://doi.org/10.1016/j.jbc.2023.105056

Raics, Katalin; Pirisi, Katalin; Zhuang, Bo; Fekete, Zsuzsanna; Kis-Bicskei, Nikolett; Pecsi, Ildiko; Ujfalusi, Kinga Pozsonyi; Telek, Elek; Li, Yin; Collado, Jinnette Tolentino; et al (August 2023, Journal of Biological Chemistry)

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